منابع مشابه
Mapping and manipulating neural circuits in the fly brain.
Drosophila is a marvelous system to study the underlying principles that govern how neural circuits govern behaviors. The scale of the fly brain (approximately 100,000 neurons) and the complexity of the behaviors the fly can perform make it a tractable experimental model organism. In addition, 100 years and hundreds of labs have contributed to an extensive array of tools and techniques that can...
متن کاملChapter 3 - Mapping and Manipulating Neural Circuits in the Fly Brain
Drosophila is a marvelous system to study the underlying principles that govern how neural circuits govern behaviors. The scale of the fly brain ( 100,000 neurons) and the complexity of the behaviors the fly can perform make it a tractable experimental model organism. In addition, 100 years and hundreds of labs have contributed to an extensive array of tools and techniques that can be used to d...
متن کاملFly MARCM and mouse MADM: genetic methods of labeling and manipulating single neurons.
The Golgi staining method has served neuroscience well for more than a century. In this assay I review recent progresses using genetic methods to recapitulate and extend the Golgi staining method. These methods enable new discoveries on organization and development of neuronal circuits in the fly and mouse brains.
متن کاملManipulating the Plasmodium genome.
Genome manipulation, the primary tool for assigning function to sequence, will be essential for understanding Plasmodium biology and malaria pathogenesis in molecular terms. The first success in transfecting Plasmodium was reported almost ten years ago. Gene-targeting studies have since flourished, as Plasmodium is haploid and integrates DNA only by homologous recombination. These studies have ...
متن کاملManipulating the Gut Flora
The gastrointestinal (GI) tract represents a complex ecosystem in which a balance exists between the intestinal microflora and the host. The microflora comprises predominantly of facultative anaerobes e.g. lactobacillus and obligate anaerobes e.g. bifidobacterium. Aerobic organisms are not present in the GI tract of healthy individuals except Pseudomonas in very small numbers. Most of the gut m...
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ژورنال
عنوان ژورنال: Science
سال: 2017
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.355.6332.1387-d